1. Drug discovery, Therapeutic Peptide designing, Cancer diagnosis, Molecular dynamics simulation of Proteins and DNA.

1. Development of Biochemical assays for cancer diagnosis

2. CADD- Drug designing- Screening and characterization of novel inhibitor molecules.

3. Designing nanocages and nanofibers for drug delivery

4. Homology modelling and Molecular Dynamics Simulation of biomolecules

5. Designing and engineering peptides for therapeutics

1. PhD thesis work titled Role of human RAD51 paralogue RAD51C in DNA alkylation repair was reported in various newspapers including Times of India, The Hindu, The New Indian Express and NDTV (News dated 26th December 2019).

2. Received Excellence in research award IIT Hyderabad for the year 2017, 2018 and 2020 .

Research

1. Postdoctoral researcher at IIT Hyderabad from January 2020 to July 2020.

1. Dey, Nibedita, Gopalakrishnan Kumar, A. S. Vickram, Monisha Mohan, Reeta Rani Singhania, Anil Kumar Patel, Cheng-Di Dong, K. Anbarasu, S. Thanigaivel, and Vinoth Kumar Ponnusamy. "Nanotechnology-assisted production of value-added biopotent energy-yielding products from lignocellulosic biomass refinery–A review." Bioresource Technology (2021): 126171. (DOI: 10.1016/j.biortech.2021.126171) (ISSN no: 0960-8524) (Impact factor: 9.642)

2. Khadake, Shivaji Narayan, Shaik Karamathulla, Tapan Kumar Jena, Mohan Monisha, Nikhil Kumar Tuti, Faiz Ahmed Khan, and Roy Anindya. "Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues." Bioorganic & Medicinal Chemistry Letters 39 (2021): 127883. (DOI: 10.1016/j.bmcl.2021.127883) (ISSN no: 0960-894X) (Impact factor: 2.572)

3. Mohan, Monisha, Mulla Althafh Hussain, Faiz Ahmed Khan, and Roy Anindya. "Symmetrical and un-symmetrical curcumin analogues as selective COX-1 and COX-2 inhibitor." European Journal of Pharmaceutical Sciences 160 (2021): 105743. (DOI: 10.1016/j.ejps.2021.105743) (ISSN no: 0022-3549) (Impact factor: 4.23)

4. Mohan Monisha, Deepa Akula, Arun Dhillon, Arun Goyal, and Roy Anindya. "Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase." Nucleic acids research (2019). (DOI: 10.1093/nar/gkz938) (ISSN no: 1362-4962) (Impact factor: 16.971)

5. Sharma Mukul, Deepa Akula, Monisha Mohan, Richa Nigam, Madhusmita Das, and Roy Anindya. "Heteroexpression of Mycobacterium leprae hypothetical protein ML0190 provides protection against DNA-alkylating agent methyl methanesulfonate." Biochemical and biophysical research communications 509, no. 3 (2019): 779-783. (DOI: 10.1016/j.bbrc.2018.12.184) (ISSN no: 0006-291X) (Impact factor: 3.575)

6. Tomar, Gaurav S., Gyaninder P. Singh, Dhruba Lahkar, Kangana Sengar, Richa Nigam, Monisha Mohan, and Roy Anindya. "New biomarkers in brain trauma." Clinica Chimica Acta 487 (2018): 325-329. (DOI: 10.1016/j.cca.2018.10.025) (ISSN no: 0009-8981) (Impact factor: 3.786)

7. Nigam Richa*, Monisha Mohan*, Gururaj Shivange, Pranjal Kumar Dewangan, and Roy Anindya. "Escherichia coli AlkB interacts with single-stranded DNA binding protein SSB by an intrinsically disordered region of SSB." Molecular biology reports 45, no. 5 (2018): 865-870. (* equal contribution) (DOI: 10.1007/s11033-018-4232-6) (ISSN no: 1573-4978) (Impact factor: 2.316)

8. Singh Gyaninder Pal, Richa Nigam, Gaurav Singh Tomar, Mohan Monisha, Sanjeev Kumar Bhoi, S. Arulselvi, Kangana Sengar, Deepa Akula, Prashanth Panta, and Roy Anindya. "Early and rapid detection of UCHL1 in the serum of brain-trauma patients: a novel gold nanoparticle-based method for diagnosing the severity of brain injury." Analyst 143, no. 14 (2018): 3366-3373. (DOI: 10.1039/c8an00533h) (ISSN no: 1364-5528) (Impact factor: 4.616)

9. Mohan Monisha, Vishal Pandya, and Roy Anindya. "Escherichia coli AlkB and single-stranded DNA binding protein SSB interaction explored by Molecular Dynamics Simulation." Journal of Molecular Graphics and Modelling 84 (2018): 29-35. (DOI: 10.1016/j.jmgm.2018.05.007) (ISSN no: 1093-3263) (Impact factor: 2.518)

10. Shivange Gururaj, Mohan Monisha, Richa Nigam, Naveena Kodipelli, and Roy Anindya. "RecA stimulates AlkB-mediated direct repair of DNA adducts." Nucleic acids research 44, no. 18 (2016): 8754-8763. (DOI: 10.1093/nar/gkw611) (ISSN no: 1362-4962) (Impact factor: 16.971)

11. Kumari Rina, Sumit Singh, Mohan Monisha, Sourav Bhowmick, Anindya Roy, Neeladri Das, and Prolay Das. "Hierarchical coassembly of DNA–triptycene hybrid molecular building blocks and zinc protoporphyrin IX." Beilstein journal of nanotechnology 7, no. 1 (2016): 697-707. (DOI: 10.3762/bjnano.7.62) (ISSN no: 2190-4286) (Impact factor: 2.968)

12. Singh Vandana, Mohan Monisha, Roy Anindya, and Prolay Das. "Self-assembled nanocages from DNA–protoporphyrin hybrid molecules." RSC Advances 5, no. 108 (2015): 89025-89029. (DOI: 10.1039/C5RA16851A) (ISSN no: 2046-2069) (Impact factor: 3.361)

13. Shivange Gururaj, Naveena Kodipelli, Mohan Monisha, and Roy Anindya. "A role for Saccharomyces cerevisiae Tpa1 protein in direct alkylation repair." Journal of Biological Chemistry 289, no. 52 (2014): 35939-35952. (DOI: 10.1074/jbc.M114.590216) (ISSN no: 0021-9258) (Impact factor: 5.157)

1. Richa Nigam, Monisha Mohan, Roy Anindya, Escherichia coli single-stranded DNA binding protein SSB binds to AlkB and promotes DNA repair. FEBS Open Bio, 8: 28135. Doi:10.1002/2211-5463.12453

2. Monisha Mohan and Roy Anindya, “Homologous recombination protein RAD51C promotes ALKBH3 mediated repair of DNA alkylation damage”, 27th Federation of Asian and Oceanian Biochemistry and Molecular Biology Conference in conjunction with the 44th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology & International Union of Biochemistry and Molecular Biology Special Symposia, 19 - 22 August 2019, Malaysia.